Here we present the 6-second resolution raw Thermosalinograph (TSG) data collected on the Integrated Ecosystem Programme: Southern Benguela (IEP:SB) cruise on the Algoa Voyage 282 between 10 May and 18 May 2022. A SeaBird SBE45 Thermosalinograph (TSG) is used to opportunistically collect underway near-surface temperature and conductivity measurements during research and monitoring cruises. Water is continuously pumped to the TSG from an intake located in the hull of the vessel, and the observations are continuously interfaced with navigational information. A temperature sensor close to the intake provides temperature measurements of the incoming water (T1). The temperature of the water inside the conductivity cell (T2) is used to accurately compute salinity (S) from the conductivity measurements (C). The IEP:SB in 2013 consolidated a long-term, multi-decadal time-series (from 1951 onward) of information for this important region and has continued monitoring in the form of the IEP:SB. The programme is a multi-disciplinary, collaborative and capacity building platform undertaking relevant science, including updating technology, with the aim to develop ecosystem indicators that can be used to effectively monitor and understand the Southern Benguela. These include physical, chemical, planktonic, microbial, seabird, marine mammal, benthic and pollution (plastic) ecosystem indicators as required by ecosystem-based management regarding the following priorities: ocean warming, ocean acidification, trophic functioning, pollution and water quality. It is on-going monitoring programme.